학술논문

Overexpression of the 78-kDa Glucose-regulated Protein/Immunoglobulin-binding Protein (GRP78/BiP) Inhibits Tissue Factor Procoagulant Activity.
Document Type
Article
Source
Journal of Biological Chemistry. 5/9/2003, Vol. 278 Issue 19, p17438. 10p. 7 Color Photographs, 1 Chart, 20 Graphs.
Subject
*THROMBIN
*GLUCOSE
*GENE transfection
Language
ISSN
0021-9258
Abstract
Reports that cells overexpressing GRP78/BiP exhibited significant decreases in cell surface-mediated thrombin generation, prothrombin consumption and the formation fo thrombin-inhibitor complexes. Comparison with wild-type or vector-transfected cells; Cell culture and treatment conditions; Biotinylation of cell surface proteins.