학술논문
A petavoxel fragment of human cerebral cortex reconstructed at nanoscale resolution.
Document Type
Article
Author
Shapson-Coe, Alexander; Januszewski, Michał; Berger, Daniel R.; Pope, Art; Yuelong Wu; Blakely, Tim; Schalek, Richard L.; Li, Peter H.; Shuohong Wang; Maitin-Shepard, Jeremy; Karlupia, Neha; Dorkenwald, Sven; Sjostedt, Evelina; Leavitt, Laramie; Lee, Dongil; Troidl, Jakob; Collman, Forrest; Bailey, Luke; Fitzmaurice, Angerica; Kar, Rohin
Source
Subject
*NEURAL circuitry
*TEMPORAL lobe
*HUMAN beings
*NEUROGLIA
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Language
ISSN
0036-8075
Abstract
The article presents a groundbreaking study where a petavoxel fragment of human cerebral cortex was reconstructed at nanoscale resolution, revealing intricate details of neural circuits and synaptic connections. Topics discussed include the methodology of obtaining high-quality human brain tissue, the generation of a petascale dataset through high-throughput serial section electron microscopy, and the identification of previously unrecognized neuronal classes and multisynaptic connections.