학술논문
Early oral immunotherapy in infants with cow's milk protein allergy.
Document Type
Article
Author
Source
Subject
*MILK allergy
*MILK proteins
*MILKING
*INFANTS
*IMMUNOTHERAPY
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Language
ISSN
0905-6157
Abstract
Cow's milk allergy (CMA) is the most frequent food allergy in the first years of life, with prevalence rates estimated in the range of 2%-3%.[[1]] With the aim of reducing the risk of allergic reactions for accidental exposures to cow's milk (CM) proteins and of favouring the regain of clinical tolerance, strategies of controlled oral exposure to CM have been developed as immunotherapy for the treatment of children with established food allergy.[[3]] However, available data on the use of oral immunotherapy in infants with food allergy are very limited. Determination of IgE- and IgG4-specific CM and CM proteins was performed at baseline and repeated approximately two months after the start and at the completion of the protocol. During in-hospital administration of doubled dose, seven children (10%) presented at least an allergic reaction and we recorded a total of 13 allergic reactions, classes 1-3. Acute allergic reactions in children with AEDS after prolonged cow's milk elimination diets. [Extracted from the article]