학술논문
Pseudoangiomatous Stromal Hyperplasia (PASH) of the Breast: An Uncommon Finding in an Uncommon Patient.
Document Type
Article
Author
Source
Subject
*BREAST
*THERAPEUTICS
*HYPERPLASIA
*ORAL contraceptives
*MENSTRUAL cycle
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Language
ISSN
1941-5923
Abstract
Objective: Unknown ethiology Background: Pseudoangiomatous stromal hyperplasia (PASH) is an uncommon benign breast lesion. Case Report: PASH is reported in a young female in treatment for neurological diseases with multi-drug therapy (clonazepam, valproate and risperidone). Her menstrual cycles are irregular, and she reached menarche very late. Conclusions: The higher PASH prevalence in premenopausal woman (the majority of whom are actively taking oral contraceptive pills), in 24% to 47% of men with gynecomastia and during pregnancy supports a hormonal etiology; the interaction between clonazepam, valproate, risperidone and progesterone could increase the level of progesterone that could stimulate PASH growth. [ABSTRACT FROM AUTHOR]