학술논문

Different initiation of pre-TCR and gamma delta TCR signalling.
Document Type
Article
Source
Nature. 8/3/2000, Vol. 406 Issue 6795, p524. 4p. 5 Color Photographs, 5 Black and White Photographs.
Subject
*T cell receptors
*T cells
*GLYCOLIPIDS
*PROTEIN kinases
*IMMUNOLOGY
*CHEMICAL structure
Language
ISSN
0028-0836
Abstract
Discusses the lineage of T lymphocytes in the immune system. Use of confocal microscopy and biochemistry to analyze the initiation of signalling that the pre-T-cell receptor (TCR) genes, but not the gamma delta TCR, colocalizes with the p56...Src kinase into glycolipid-enriched membrane domains without ligation; Indication of differences in protein signalling.