학술논문
Intrahost Monkeypox Virus Genome Variation in Patient with Early Infection, Finland, 2022.
Document Type
Article
Author
Vauhkonen, Hanna; Kallio-Kokko, Hannimari; Hiltunen-Back, Eija; Lönnqvist, Lasse; Leppäaho-Lakka, Jaana; Mannonen, Laura; Kant, Ravi; Sironen, Tarja; Kurkela, Satu; Lappalainen, Maija; Zorec, Tomaž Mark; Zakotnik, Samo; Vlaj, Doroteja; Korva, Miša; Avšič-Županc, Tatjana; Poljak, Mario; Smura, Teemu; Vapalahti, Olli
Source
Subject
*VIRAL variation
*MONKEYPOX
*VIRAL genomes
*INFECTION
*MIXED infections
*
*
*
*
Language
ISSN
1080-6040
Abstract
Monkeypox virus was imported into Finland during late May–early June 2022. Intrahost viral genome variation in a sample from 1 patient comprised a major variant with 3 lineage B.1.3–specific mutations and a minor variant with ancestral B.1 nucleotides. Results suggest either ongoing APOBEC3 enzyme–mediated evolution or co-infection. [ABSTRACT FROM AUTHOR]