학술논문

Evaluation of Polymerase Chain Reaction for Group B Streptococcus Detection Using an Improved Culture Method.
Document Type
Article
Source
Obstetrics & Gynecology. Sep2006, Vol. 108 Issue 3 part 1, p488-491. 4p. 1 Chart.
Subject
*STREPTOCOCCAL diseases
*DIAGNOSTIC use of polymerase chain reaction
*DIAGNOSTIC bacteriology
*MOLECULAR diagnosis
*GYNECOLOGY
Language
ISSN
0029-7844
Abstract
The study evaluates the diagnostic accuracy of real-time polymerase chain reaction for detection of group B streptococci. The sensitivity of the RT-PCR assay was found to be 86.8 percent, while the specificity was 95.2 percent. The false-negative rate of the RT-PCR assay was 13.2 percent, making it a substandard assessment tool in the office setting.