학술논문

Molecular characterization of adult IRF4 large B-cell lymphoma with spontaneous remission.
Document Type
Article
Source
Acta Oncologica. Aug2023, Vol. 62 Issue 8, p948-952. 5p. 1 Color Photograph, 1 Diagram, 1 Graph.
Subject
*REVERSE transcriptase polymerase chain reaction
*BIOPSY
*SEQUENCE analysis
*MICROSCOPY
*IMMUNOHISTOCHEMISTRY
*B cell lymphoma
*POSITRON emission tomography computed tomography
*LYMPH nodes
*MACHINE learning
*NF-kappa B
*CHROMOSOME banding
*LYMPHATIC diseases
*BIOINFORMATICS
*GENE expression profiling
*SPONTANEOUS cancer regression
*CHROMOSOME abnormalities
*RADIOPHARMACEUTICALS
*FLUORESCENCE in situ hybridization
*GENETIC markers
*TUMOR markers
*DEOXY sugars
*NECK
Language
ISSN
0284-186X
Abstract
The article presents the case of a high-grade IRF4-Large B cell lymphoma (LBCL) with spontaneous remission resulting from dysregulation by IGL translocation. Topics discussed include medical investigation on a 34-year old male patient presented for an isolated right cervical lymphadenopathy, what R-banding analysis of chromosomes from nodal tissue obtained by short-term culture without mitogens revealed, and overview on gene expression profiling and mutational profiling.