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Colonoscopy, Colon cancer, Cancer screening Patients undergoing initial colonoscopy within a prospectively maintained colonoscopy quality database from January 2012 to April 2020 within a large group practice were identified. Keywords: Colonoscopy; Colon cancer; Cancer screening EN Colonoscopy Colon cancer Cancer screening 1513 1515 3 07/21/22 20220701 NES 220701 Introduction The global incidence of new colorectal cancers has been steadily declining over several decades, largely attributed to widespread efforts to increase colorectal cancer screening.[1],[2] In patients presenting with symptoms such as blood per rectum or altered bowel habits, colonoscopy is considered the appropriate test to diagnose and potentially treat colonic pathology. [Extracted from the article]