학술논문
Palmar-plantar erythrodysesthesia: An uncommon adverse effect of everolimus.
Document Type
Case Study
Source
Subject
*EVEROLIMUS
*METASTATIC breast cancer
*PATIENT management
*HORMONE therapy
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Language
ISSN
0971-5851
Abstract
Mammalian target of rapamycin inhibitor everolimus is a novel agent used in endocrine therapy resistant hormone receptor positive metastatic breast cancer. Its use has been associated with clinically significant improvement in the otherwise dismal outcomes of this subset of patients. Rash is a common adverse effect associated with everolimus. However, Hand-foot syndrome is an uncommon toxicity with the use of this drug. We report a case of Grade 3 hand-foot syndrome following institution of everolimus therapy and describe its successful management. [ABSTRACT FROM AUTHOR]