부산대학교 도서관

In chimeras such as Karen Keegan, cells negotiate the differences between the two genomes coming together to create one body. Life From a Cell's Point of View At a certain point in life's history, cells invented plants and animals by gaining the capacity to use genes to cooperate and communicate with each other on a permanent basis. For example, gene-editing interventions using CRISPR (an acronym for "clustered regularly interspaced short palindromic repeats") have been shown to repair a single change in the DNA for the beta globin gene (HBB) that produces sickle cell anemia and thereby restore the health of individuals. Mapping gene mutations to cell malfunctions may help us understand what happens when a gene is faulty or absent, but more often than you think, the observation doesn't tell us how cells use the normal form of the gene to make normal tissues and organs. [Extracted from the article]