학술논문

Herpes simplex virus type 2: a cause of acute retinal necrosis syndrome.

Document Type

Journal Article

Author

Markomichelakis, Nikos N.; Zafirakis, Panayotis; Karambogia-Karefillidi, Paraskeui; Drakoulis, Nikolaos; Vagiakou-Boudri, Eleni; Paterakis, George; Apostolopoulos, Michael; Markomichelakis, N N; Zafirakis, P; Karambogia-Karefillidi, P; Drakoulis, N; Vagiakou-Boudri, E; Paterakis, G; Apostolopoulos, M

Source

Ocular Immunology & Inflammation. Jun2001, Vol. 9 Issue 2, p103-109. 7p.

Subject

*RETINAL diseases
*HERPES simplex

Language

ISSN

0927-3948

Abstract

Purpose: To describe a case of herpes simplex virus type 2 (HSV-2) acute retinal necrosis syndrome (ARN) in a 13-year-old immunocompetent girl.Methods: Polymerase chain reaction (PCR), cultures, flow cytometry, and cytology were performed on the vitreous sample.Results: Both PCR studies and vitreous cultures revealed HSV-2 as the cause of ARN. Flow cytometry showed CD4+, CD8+, and natural killer cells. The visual outcome of the patient was 20/200.Conclusion: Successful culture of HSV-2 from the vitreous specimen in a patient with ARN proved HSV-2 to be one of the causes of ARN. The successful culture of HSV-2 has not been previously reported. [ABSTRACT FROM AUTHOR]

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