학술논문
Effect of high-dose allopurinol on exercise in patients with chronic stable angina: a randomised, placebo controlled crossover trial.
Document Type
Article
Source
Subject
*DRUG dosage
*BLIND experiment
*PLACEBOS
*EXERCISE
*CORONARY heart disease treatment
ANGINA pectoris treatment
*
*
*
*
Language
ISSN
0140-6736
Abstract
The article discusses a study which investigated the link between high-dose allopurinol and prolonged exercise capability in patients with chronic stable angina. The double-blind and randomised placebo-controlled study involved 65 patients aged 18 to 85 years who are suffering from coronary artery disease and have a positive exercise tolerance test and stable chronic angina pectoris. Computer-generated randomisation was used to assign patients to allopurinol or placebo. It was found that the drug seems to be useful and well tolerated anti-ischaemic drug.