학술논문

Forkhead-like transcription factors recruit Ndd1 to the chromatin of G2/M-specific promoters.
Document Type
Article
Source
Nature. 7/6/2000, Vol. 406 Issue 6791, p94. 5p. 9 Black and White Photographs.
Subject
*CELLULAR control mechanisms
*CELL cycle
*TRANSCRIPTION factors
*GENETIC transcription
Language
ISSN
0028-0836
Abstract
Shows that a positive cell regulator, Ndd1, becomes associated with G2/M promoter regions in a manner that depends on the stage in cell cycle and that its recruitment depends on a permanent protein-DNA complex, which includes the transcription factor Fkh2. Methods; Results; Conclusion that Ndd1-Fkh2 interactions may be the transcriptionally important process targeted by Cdk activity.