학술논문

Elucidation of the structural basis of interaction of the BCR-ABL kinase inhibitor, nilotinib (Tasigna) with the human ABC drug transporter P-glycoprotein.
Document Type
Article
Source
Leukemia (08876924). Apr2014, Vol. 28 Issue 4, p961-964. 4p. 2 Diagrams.
Subject
*NILOTINIB
*PROTEIN-tyrosine kinases
*ATP-binding cassette transporters
Language
ISSN
0887-6924
Abstract
A letter to the editor is presented regarding nilotinib, imatinib and other tyrosine kinase inhibitors (TKIs) which have transporrted by the ATP-binding cassette (ABC) drug transporters P-glycoprotein (P-gp) and ABCG2.