학술논문

Breastfeeding and childhood acute otitis media: a systematic review and meta-analysis.
Document Type
Journal Article
Source
Acta Paediatrica. Dec2015 Supplement, Vol. 104, p85-95. 11p.
Subject
*BREASTFEEDING
*ACUTE otitis media
*META-analysis
*SYSTEMATIC reviews
*INFANT formulas
*DATA extraction
*RANDOM effects model
*HETEROGENEITY
*OTITIS media
*TIME
*ACUTE diseases
Language
ISSN
0803-5253
Abstract
Aim: To synthesise the evidence on the association between duration and exclusivity of breastfeeding and the risk of acute otitis media (AOM).Methods: Systematic review and meta-analysis following searching of PubMed, CINAHL and EMBASE electronic databases.Results: Twenty-four studies, all from the USA or Europe, met the inclusion criteria. In the pooled analyses, any form of breastfeeding was found to be protective for AOM in the first 2 years of life. Exclusive breastfeeding for the first 6 months was associated with the greatest protection (OR 0.57 95% CI 0.44, 0.75), followed by 'more vs less' breastfeeding (OR 0.67; 0.59, 0.76) and 'ever vs never' breastfeeding (OR 0.67; 0.56, 0.80).Conclusion: This systematic review and meta-analysis provides evidence that breastfeeding protects against AOM until 2 years of age, but protection is greater for exclusive breastfeeding and breastfeeding of longer duration. Exclusive breastfeeding during the first 6 months was associated with around a 43% reduction in ever having AOM in the first 2 years of life. After 2 years of age, there is no evidence that breastfeeding protects against AOM; however, there were few studies and the evidence quality was low. [ABSTRACT FROM AUTHOR]