학술논문
Mild Aminoacylation of Indoles and Pyrroles through a Three-Component Reaction with Ynol Ethers and Sulfonyl Azides.
Document Type
Article
Author
Source
Subject
*AMINOACYLATION
*INDOLE compounds
*CHEMICAL reactions
*PYRROLES
*SULFONYL azides
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Language
ISSN
0002-7863
Abstract
An effective method for aminoacylation of indoles and pyrroles has been achieved. The transformation involves a multicomponent one-pot cascade reaction between indoles or pyrroles, ynol ethers, and sulfonyl azides, creating four different bonds regioselectively through N-sulfonyltriazole intermediates. The oxotryptamines and cwo-pyrroloethanamines are generated in moderate to high yields under mild reaction conditions. [ABSTRACT FROM AUTHOR]