학술논문
Conversion of Cyclic Ketones to 2,3-Fused Pyrroles and Substituted Indoles.
Document Type
Article
Source
Subject
*PYRROLES
*CHEMICAL synthesis
*KETONES
*CYCLIC groups
*INDOLE compounds
*RHODIUM catalysts
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Language
ISSN
0002-7863
Abstract
A highly effective synthesis of 2,3-fused pyrroles from cyclic ketones has been achieved. The transformation includes a rhodium-catalyzed reaction of 4-alkenyl-1-sulfonyl-1,2,3-triazoles featuring an unusual 4π electrocyclization. The methodology was further extended to the synthesis of indoles using a one-pot reaction starting from 1-ethynylcyclohexenes. [ABSTRACT FROM AUTHOR]