학술논문

Modern Trends in Natural Antibiotic Discovery.
Document Type
Article
Source
Life (2075-1729). May2023, Vol. 13 Issue 5, p1073. 29p.
Subject
*MOLECULAR biology
*SCIENTIFIC method
*BIOACTIVE compounds
*DRUG development
*ANTIBIOTICS
*NATURAL products
Language
ISSN
2075-1729
Abstract
Natural scaffolds remain an important basis for drug development. Therefore, approaches to natural bioactive compound discovery attract significant attention. In this account, we summarize modern and emerging trends in the screening and identification of natural antibiotics. The methods are divided into three large groups: approaches based on microbiology, chemistry, and molecular biology. The scientific potential of the methods is illustrated with the most prominent and recent results. [ABSTRACT FROM AUTHOR]