학술논문
Morphological, immunological and immunocytochemical identification of lymphocytes extracted from cutaneous infiltrates.
Document Type
Article
Author
Source
Subject
*IMMUNOLOGY
*LYMPHOCYTES
*T cells
*B cells
*IMMUNOGLOBULINS
*BLOOD proteins
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*
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Language
ISSN
0009-9104
Abstract
The identification of mononuclear cells extracted from various skin disorders has been investigated and the relative amount of B and T cells determined according to various assays such as E-rosette test, EAC-rosette test, FITC and peroxidase anti-immunoglobulin conjugates. It has been found that: (a) there were two different patterns of distribution of the cells in the infiltrates; one with a T/B ratio above 3 (closest to a delayed type reaction), the other with a T/B ratio below 2. (b) The morphological appearance of tissue lymphocytes differs from that of circulating lymphocytes by the presence of both membrane and cytoplasmic immunoglobulins. [ABSTRACT FROM AUTHOR]