학술논문

Ichthyosiform erythroderma and cardiomyopathy: report of two cases and review of the literature.
Document Type
Article
Source
British Journal of Dermatology. Dec1998, Vol. 139 Issue 6, p1055-1059. 5p. 2 Diagrams.
Subject
*SKIN inflammation
*JUVENILE diseases
*CARDIOMYOPATHIES
Language
ISSN
0007-0963
Abstract
We report two children with ichthyosiform erythroderma who at the ages of 9 weeks and 8 years, respectively, developed dilated cardiomyopathy, which was fatal in one and required heart transplantation in the other. A link between these conditions is considered likely, either as a primary genetic syndrome or secondary to micronutrient deficiency and/or infection. Owing to its insidious onset, cardiomyopathy may be overlooked, or symptoms attributed to the other conditions such as severe infections and failure to thrive that are common in these patients. We therefore recommend that children with congenital erythroderma are monitored closely, clinically and with echocardiography, for cardiomyopathy. [ABSTRACT FROM AUTHOR]