학술논문
Outcomes of COVID-19 patients with comorbidities in southwest Nigeria.
Document Type
Article
Author
Osibogun, Akin; Balogun, Mobolanle; Abayomi, Akin; Idris, Jide; Kuyinu, Yetunde; Odukoya, Oluwakemi; Wright, Ololade; Adeseun, Remi; Mutiu, Bamidele; Saka, Babatunde; Osa, Nike; Lajide, Dayo; Abdus-Salam, Ismael; Osikomaiya, Bodunrin; Onasanya, Oluwatosin; Adebayo, Bisola; Oshodi, Yewande; Adesola, Sunday; Adejumo, Olu; Erinoso, Olufemi
Source
Subject
*COVID-19
*COMORBIDITY
*DEATH rate
*AFRICANS
*HYPERTENSION
*MEDICAL records
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Language
ISSN
1932-6203
Abstract
Background: Data on the comorbidities that result in negative outcomes for people with COVID-19 are currently scarce for African populations. This study identifies comorbidities that predict death among a large sample of COVID-19 patients from Nigeria. Methods: This was a retrospective analysis of medical records for 2184 laboratory confirmed cases of COVID-19 in Lagos, southwest Nigeria. Extracted data included age, sex, severity of condition at presentation and self-reported comorbidities. The outcomes of interest were death or discharge from facility. Results: Most of the cases were male (65.8%) and the median age was 43 years (IQR: 33–55). Four hundred and ninety-two patients (22.5%) had at least one comorbidity and the most common amongst them were hypertension (74.2%) and diabetes (30.3%). The mortality rate was 3.3% and a significantly higher proportion of patients with comorbidities died compared to those with none. The comorbidities that predicted death were hypertension (OR: 2.21, 95%CI: 1.22–4.01), diabetes (OR: 3.69, 95% CI: 1.99–6.85), renal disease (OR: 12.53, 95%CI: 1.97–79.56), cancer (OR: 14.12, 95% CI: 2.03–98.19) and HIV (OR: 1.77–84.15]. Conclusion: Comorbidities are prevalent and the associated risk of death is high among COVID-19 patients in Lagos, Nigeria. Public enlightenment, early identification and targeted care for COVID-19 cases with comorbidities are recommended as the pandemic evolves. [ABSTRACT FROM AUTHOR]