학술논문
Liver stiffness measurement by transient elastography can predict outcome after hepatic resection for hepatitis C virus-induced hepatocellular carcinoma.
Document Type
Article
Author
Source
Subject
*ACOUSTIC radiation force impulse imaging
*HEPATOCELLULAR carcinoma
*RECEIVER operating characteristic curves
*LIVER failure
*ELASTOGRAPHY
*HEPATITIS C virus
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Language
ISSN
1110-1121
Abstract
Objective The aim was to assess the predictive value of liver stiffness (LS) measurement by transient elastography (FibroScan) on the risk of postoperative hepatic decompensation in patients with cirrhosis undergoing hepatectomy for hepatocellular carcinoma (HCC). Patients and methods This prospective study was conducted on 40 adult patients with hepatitis C virus (HCV)-related HCC eligible for hepatic resection between 2015 and 2017. LS was prospectively measured for all patients. Preoperative and postoperative variables (patients' demographics, comorbidities, laboratory, and radiological data) were collected. Results Hepatic insufficiency occurred in 35% of patients (14 patients). Receiver operating characteristic curve analysis of preoperative LS measurement identified a value equal to or higher than 15.4 KPa as the best cutoff value for predicting postoperative hepatic decompensation, with a sensitivity of 100%, specificity 100%, a positive predictive value of 100%, and a negative predictive value of 100%. Conclusion LS measured by transient elastography (FibroScan) is a potentially reliable tool to predict postoperative hepatic decompensation in patients undergoing surgical resection for HCC. [ABSTRACT FROM AUTHOR]