학술논문
Photocatalytic generation of 1,4-disubstituted 1,2,3-triazoles under metal, oxidant and azide-free conditions.
Document Type
Article
Source
Subject
*TRIAZOLES
*RING formation (Chemistry)
*CHEMICAL reactions
*AMINES
*RADICALS
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Language
ISSN
2666-5549
Abstract
Available online A mild and efficient photocatalytic-induced radical method has been developed for [4 þ 1] cycloaddition reaction of 1,4-disubstituted 1,2,3-triazoles with N-tosylhydrazides and primary amines. The reaction is catalyzed by 20 mol% of I2 under metal, azide and oxidant-free conditions. The method is based upon the photocatalytic generation of allyl-type radicals, followed by the iodine-catalyzed production of azoalkenes, which react rapidly with various anilines. [ABSTRACT FROM AUTHOR]