부산대학교 도서관

The preparation of chromene derivatives were performed by using four component reactions 2-hydroxyacetophenone or 2-aminoacetophenone, dimethyl carbonate, Meldrum's acid and aldehyde or ketones in the presence of catalytic amounts of Ag@KF/Natrolite NPs as a high-performance catalyst in water at room temperature. Due to having chromene core, we investigate antioxidant property of some synthesized compounds by diphenyl-picrylhydrazine (DPPH) radical trapping and power of ferric reduction experiment. Furthermore, the disk diffusion test on Gram-positive and -negative bacteria are utilized for investigation of antimicrobial activity of some chromenes. The achieved outcomes of this experiment demonstrate that these synthesized compounds could prevent from growth of bacteria. Short time of reaction, high yields of product, easy separation of catalyst and products are some benefits of this process. [ABSTRACT FROM AUTHOR]