학술논문
Recreational marathon running does not cause exercise-induced left ventricular hypertrabeculation.
Document Type
Article
Author
Source
Subject
*MARATHON running
*CARDIAC magnetic resonance imaging
*
Language
ISSN
0167-5273
Abstract
Marathon running in novices represents a natural experiment of short-term cardiovascular remodeling in response to running training. We examine whether this stimulus can produce exercise-induced left ventricular (LV) trabeculation. Sixty-eight novice marathon runners aged 29.5 ± 3.2 years had indices of LV trabeculation measured by echocardiography and cardiac magnetic resonance imaging 6 months before and 2 weeks after the 2016 London Marathon race, in a prospective longitudinal study. After 17 weeks unsupervised marathon training, indices of LV trabeculation were essentially unchanged. Despite satisfactory inter-observer agreement in most methods of trabeculation measurement, criteria defining abnormally hypertrabeculated cases were discordant with each other. LV hypertrabeculation was a frequent finding in young, healthy individuals with no subject demonstrating clear evidence of a cardiomyopathy. Training for a first marathon does not induce LV trabeculation. It remains unclear whether prolonged, high-dose exercise can create de novo trabeculation or expose concealed trabeculation. Applying cut off values from published LV noncompaction cardiomyopathy criteria to young, healthy individuals risks over-diagnosis. • Athletes often show excessive ventricular trabeculation. • It is unknown whether left ventricular noncompaction cardiomyopathy can be acquired. • It is proposed that trabeculation may result from athletic remodeling to exercise. • Imaging is prone to overdiagnosis of left ventricular noncompaction cardiomyopathy. • Recreational marathon running does not increase left ventricular trabeculation. [ABSTRACT FROM AUTHOR]