학술논문

Updates on radiotherapy-immunotherapy combinations: Proceedings of 6th annual ImmunoRad conference.
Document Type
article
Source
Oncoimmunology. 12(1)
Subject
Humans
Neoplasms
Immunotherapy
Combined Modality Therapy
FLASH radiotherapy
dose and fractionation
immune checkpoint inhibitors
immunomodulators
lymph node sparing
tumor-associated macrophages
Immunization
Cancer
Vaccine Related
Immunology
Oncology and Carcinogenesis
Language
Abstract
Focal radiation therapy (RT) has attracted considerable attention as a combinatorial partner for immunotherapy (IT), largely reflecting a well-defined, predictable safety profile and at least some potential for immunostimulation. However, only a few RT-IT combinations have been tested successfully in patients with cancer, highlighting the urgent need for an improved understanding of the interaction between RT and IT in both preclinical and clinical scenarios. Every year since 2016, ImmunoRad gathers experts working at the interface between RT and IT to provide a forum for education and discussion, with the ultimate goal of fostering progress in the field at both preclinical and clinical levels. Here, we summarize the key concepts and findings presented at the Sixth Annual ImmunoRad conference.