학술논문
Recruitment of a multi‐site randomized controlled trial of aerobic exercise for older adults with amnestic mild cognitive impairment: The EXERT trial
Document Type
article
Author
Shadyab, Aladdin H; LaCroix, Andrea Z; Feldman, Howard H; van Dyck, Christopher H; Okonkwo, Ozioma C; Tam, Steven P; Fairchild, J Kaci; Welsh‐Bohmer, Kathleen A; Matthews, Genevieve; Bennett, Daniel; Shadyab, Alexandre A; Schafer, Kimberly A; Morrison, Rosemary H; Kipperman, Sean A; Mason, Jennifer; Tan, Donna; Thomas, Ronald G; Cotman, Carl W; Baker, Laura D; Group, for the ADCS EXERT Study
Source
Alzheimer's & Dementia. 17(11)
Subject
Language
Abstract
IntroductionEffective strategies to recruit older adults with mild cognitive impairment (MCI) into nonpharmacological intervention trials are lacking.MethodsRecruitment for EXERT, a multisite randomized controlled 18-month trial examining the effects of aerobic exercise on cognitive trajectory in adults with amnestic MCI, involved a diverse portfolio of strategies to enroll 296 participants.ResultsRecruitment occurred September 2016 through March 2020 and was initially slow. After mass mailings of 490,323 age- and geo-targeted infographic postcards and brochures, recruitment rates increased substantially, peaking at 16 randomizations/month in early 2020. Mass mailings accounted for 52% of randomized participants, whereas 25% were recruited from memory clinic rosters, electronic health records, and national and local registries. Other sources included news broadcasts, public service announcements (PSA), local advertising, and community presentations.DiscussionAge- and geo-targeted mass mailing of infographic materials was the most effective approach in recruiting older adults with amnestic MCI into an 18-month exercise trial.