학술논문

Early Neuromuscular Blockade in the Acute Respiratory Distress Syndrome
Document Type
article
Source
New England Journal of Medicine. 380(21)
Subject
Clinical Research
Lung
Bioengineering
Cardiovascular
Acute Respiratory Distress Syndrome
Rare Diseases
Clinical Trials and Supportive Activities
Respiratory
Good Health and Well Being
Adult
Aged
Atracurium
Combined Modality Therapy
Conscious Sedation
Female
Hospital Mortality
Humans
Male
Middle Aged
Neuromuscular Blockade
Neuromuscular Blocking Agents
Positive-Pressure Respiration
Respiratory Distress Syndrome
Treatment Failure
National Heart
Lung
and Blood Institute PETAL Clinical Trials Network
Medical and Health Sciences
General & Internal Medicine
Language
Abstract
BackgroundThe benefits of early continuous neuromuscular blockade in patients with acute respiratory distress syndrome (ARDS) who are receiving mechanical ventilation remain unclear.MethodsWe randomly assigned patients with moderate-to-severe ARDS (defined by a ratio of the partial pressure of arterial oxygen to the fraction of inspired oxygen of