학술논문
Abstract 16435: Contemporary In-Hospital Outcomes of Chronic Total Occlusion Interventions: Update From the PROGRESS-CTO (prospective Global Registry for the Study of Chronic Total Occlusion Intervention) Multicenter International Registry
Document Type
Academic Journal
Author
Karacsonyi, Judit; Alaswad, Khaldoon; Karmpaliotis, Dimitrios; Krestyaninov, Oleg; Choi, James; Khatri, Jaikirshan; Jaffer, Farouc A; PATEL, MITUL P; Mahmud, Ehtisham; Doing, Anthony; Dattilo, Philip; Kandzari, David E; Koutouzis, Michalis; Tsiafoutis, Ioannis; Uretsky, Barry F; Toma, Catalin; Yeh, Robert W; Tamez, Hector; Wyman, R. Michael; Jefferson, Brian; Patel, Taral; Jaber, Wissam; Samady, Habib; Sheikh, Abdul; Malik, Bilal; Potluri, Srinivasa; Elbarouni, Basem; Love, Michael; shah, alpesh; Moses, Jeffrey; Lembo, Nicholas; Parikh, Manish; Kirtane, Ajay J; Ali, Ziad; Vemmou, Evangelia; Nikolakopoulos, Ilias; Xenogiannis, Iosif; Rangan, Bavana V; Garcia, Santiago; Banerjee, Subhash; Ungi, Imre; Brilakis, Emmanouil S
Source
Circulation. Nov 17, 2020 142(Suppl_3 Suppl 3):A16435-A16435
Subject
Language
English
ISSN
0009-7322
Abstract
Introduction: Chronic total occlusion (CTO) percutaneous coronary intervention (PCI) has been advancing due to improvement of equipment, operator experience, and techniques.Methods: We examined contemporary outcomes of CTO PCI by analyzing the clinical, angiographic, and procedural characteristics of 7,031 CTO interventions performed in 6,984 patients at 35 participating centers between 2012 and 2020.Results: Mean age was 64.5 ± 10 years and 82% of the patients were men. The patients had high prevalence of comorbidities, such as diabetes (42%), prior coronary artery bypass graft surgery (29%), prior myocardial infarction (45%), and prior heart failure (29%). The most common CTO target vessel was the right coronary artery (53%), followed by the left anterior descending artery (26%), and left circumflex artery (20%). The mean J-CTO and PROGRESS scores were 2.41 ± 1.28 and 1.09 ± 1.01, respectively. The overall technical and procedural success rates were 85.9% and 83.8% and the rate of in-hospital major cardiac adverse events (MACE) was 2.06%. Technical success and procedural success rates were lower for higher values of J-CTO and PROGRESS scores, and MACE rate was higher (Figure 1). The final successful crossing strategy was antegrade wire escalation in 53.7%, retrograde in 19.9%, and antegrade dissection reentry in 14.6%. The overall median air kerma radiation dose, contrast volume, procedure and fluoroscopy time were 2.30 (1.30, 3.90) Gray, 225 (160, 305) ml, 115 (75, 170) and 43 (26, 70) minutes, respectively.Conclusions: Using a combination of crossing strategies, high success and acceptable complication rates can be achieved in CTO PCI among various centers and patient populations.