학술논문
Metastatic Neuroendocrine Tumour in a Renal Transplant Recipient: Dual-Tracer PET-CT with 18F-FDG and 68Ga-DOTANOC in This Rare Setting
Document Type
Article
Author
Source
Nuclear Medicine and Molecular Imaging , 49(1), pp.57-60 Mar, 2015
Subject
Language
English
ISSN
1869-3482
1869-3474
1869-3474
Abstract
Recipients of renal transplant are at increased risk ofdeveloping various malignancies, especially post-transplantlymphoproliferative disorder (PTLD) and skin cancers. Neuroendocrine tumours (NET) of the gastrointestinal tracthave not been reported in this setting. Here we describe thecase of a 75-year-old male who had undergone renal transplant8 years back and now presented with significant weight lossand backache, clinically suspected as PTLD. 18FFluordeoxyglucose(18F-FDG) positron emission tomographycomputedtomography (PET-CT) showed hypermetabolic lesionsin the liver and rectum, raising the suspicion of PTLD. However, biopsy from the liver lesion showed poorly differentiatedNET. 68Ga-labelled [1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid]-1-NaI3-octreotide (68Ga-DOTANOC) PET-CT was then done, which confirmed theprimary lesion in the rectum with liver metastases.