학술논문
Effect of Fenoldopam on use of renal replacement therapy among patients with acute kidney injury after cardiac surgery
Document Type
Report
Author
Bove, Tiziana; Zuchetti, Maria C.; Frontini, Mario; Pinelli, Fulvio; Lembo, Rosalba; Calabro, Maria G.; Bellomo, Rinaldo; Verdecchia, Claudio; Baldasarri, Rubia; Pisano, Antonio; Saleh, Omar; Checco, Erika Dal; Scandroglio, Anna M.; Faita, Luana; Cariello, Claudia; Amantea, Bruno; Camata, Annamaria; Pala, Giovanni; Renzini, Massimo; Martinez, Blanca; Conte, Massimiliano; Paternosta, Gianluca; Pappalardo, Federico; Landoni, Giovanni; Galdieri, Nicola; Zangrillo, Alberto; Comis, Marco; Guarracino, Fabio; Caramelli, Fabio; Pasero, Daniela C.; Alvaro, Gabriele; Persi, Bruno; Maglioni, Enivarco
Source
JAMA, The Journal of the American Medical Association. Dec 3, 2014, Vol. 312 Issue 21, p2244, 10 p.
Subject
Language
English
ISSN
0098-7484
Abstract
The article ascertains the efficacy of Fenoldopam infusion in cardiac patients with acute kidney injury (AKI). The research conducted included 667 participants in a multicenter, randomized, double-blind, placebo-controlled, parallel group study in Italy. The findings indicated that Fenoldopam intervention did not reduce the need for renal replacement therapy or 30-day mortality risk in patients with AKI compared with the placebo-controlled group and an increased rate of hypotension was observed.