학술논문
Organometallic ruthenium complexes with thiosemicarbazone ligands: Synthesis, structure and cytotoxicity of [(I[middle dot].sup.6-p-cymene)Ru(NS)Cl].sup.+ (NS=9-anthraldehyde thiosemicarbazones)
Document Type
Report
Author
Source
Inorganic Chemistry Communications. Nov, 2009, Vol. 12 Issue 11, p1094, 5 p.
Subject
Language
English
ISSN
1387-7003
Abstract
To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.inoche.2009.08.034 Byline: Floyd A. Beckford (a), Gabriel Leblanc (a), Jeffrey Thessing (a), Michael Shaloski (a), Brian J. Frost (b), Liya Li (c), Navindra P. Seeram (c) Keywords: Thiosemicarbazones; Ruthenium-arene complex; DNA interaction; Viscometry; Cytotoxicity; Structure elucidation Abstract: A series of half-sandwich arene-ruthenium complexes of the type [(I*.sup.6-p-cymene)Ru(thiosemicarbazone)Cl].sup.+ have been synthesized and their biological activity investigated. The first structurally characterized arene-ruthenium half-sandwich complex with a thiosemicarbazone ligand is reported. Author Affiliation: (a) Science Division, Lyon College, Batesville, AR 72501, USA (b) Department of Chemistry, University of Nevada, Reno, NV 89557, USA (c) Department of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, RI 02881, USA Article History: Received 29 June 2009; Accepted 29 August 2009