학술논문
Severe SARS-CoV-2 and respiratory syncytial virus co-infection in two children
Document Type
Academic Journal
Author
Source
Folia Medica. June 30, 2023 Issue 3, p495, 5 p.
Subject
Language
English
ISSN
1314-2143
Abstract
Author(s): Andreana Angelova (corresponding author) [1,2]; Mariya Atanasova [1,2]; Kostadin Ketev [1,2]; Zeyra Halil [2]; Ivanka Paskaleva [1,2]; Gergana Lengerova [1,2]; Teodora Dimcheva [1]; Neli Korsun [3]; Mariana Murdjeva [1,2] [...]
The Coronavirus Disease 2019 (COVID-19) caused by a novel coronavirus (SARS-CoV-2) affects mainly older adults. Those with comorbidities are at a higher risk of severe disease and even death. The symptomatic infection rate of children is lower, manifestations are milder, and severe forms are scarce. We present here two children with severe COVID-19 and a respiratory syncytial virus, with the goal of emphasizing the possibility of coinfection with a severe course and a different result. The microbiological diagnosis was made using multiplex PCR. This assay not only provided an early and accurate diagnosis but also aided in the implementation of contact precautions. Further research should be done to determine the influence of coinfection on the clinical course and outcome of pediatric patients. Keywords: COVID-19, multiplex PCR, RSV, severity
The Coronavirus Disease 2019 (COVID-19) caused by a novel coronavirus (SARS-CoV-2) affects mainly older adults. Those with comorbidities are at a higher risk of severe disease and even death. The symptomatic infection rate of children is lower, manifestations are milder, and severe forms are scarce. We present here two children with severe COVID-19 and a respiratory syncytial virus, with the goal of emphasizing the possibility of coinfection with a severe course and a different result. The microbiological diagnosis was made using multiplex PCR. This assay not only provided an early and accurate diagnosis but also aided in the implementation of contact precautions. Further research should be done to determine the influence of coinfection on the clinical course and outcome of pediatric patients. Keywords: COVID-19, multiplex PCR, RSV, severity