학술논문

A CMOS fluorescent-based biosensor microarray
Document Type
Conference
Source
2009 IEEE International Solid-State Circuits Conference - Digest of Technical Papers Solid-State Circuits Conference - Digest of Technical Papers, 2009. ISSCC 2009. IEEE International. :436-437,437a Feb, 2009
Subject
Components, Circuits, Devices and Systems
Engineered Materials, Dielectrics and Plasmas
Fluorescence
Biosensors
DNA
CMOS image sensors
Biomedical measurements
Diodes
Face detection
Optical filters
Probes
Photodetectors
Language
ISSN
0193-6530
2376-8606
Abstract
Biosensors are one of the most important analytical tools in biotechnology today. These detection systems take advantage of the selective interaction and binding of certain biological molecules to identify and detect different analytes such as toxins, hormones, DNA strands, proteins, bacteria, etc. The fundamental advantage of array-based biosensors, which compensates for their limited SNR and detection dynamic range [1], is their capability to detect multiple analytes simultaneously in parallel [2]. Today, densely packed biosensor arrays (i.e., microarrays) that detect hundreds or even thousands of different analytes are an integral part of biotechnology.