부산대학교 도서관

Purpose: The aim of study was to evaluate the use of Antibiotics at the Kimpese EMI hospital in Democratic Republic of Congo, in order to contribute to the fight against antibiotic resistance. On the one hand, they cure even the most severe infections, but on the other hand, they are at the base of the antibiotic resistance. This last, is a scourge of the hour because at the base of morbidity and mortality in many nations. Our research questions were: Is the use of antibiotics effective in EMI hospital? Are they part of the most used drugs? Are they prescribed without bacteriological proof? Methods & Materials: This was a descriptive cross-sectional study of hospitalized patients, from 28 March to 7 June 2020. Information on socio-demographic characteristics, clinical and laboratory results and antibiotic use were recorded. The departments of surgery, gynaeco-obstetrics, internal medicine, ophthalmology, orthotraumatology and paediatrics were involved. The population was 1004 participants during the study period. The analysis was performed with STATA software version 14.1. 4 physicians were recruited to collect data using a questionnaire. Results: Of drugs prescribed to hospitalized patients, with 1004, 53% were antibiotics, followed by antimalarials 10%. Their use was, respectively in Orthotraumatology 27.2%, Gynaeco-obstetrics 19.2%, Surgery 16.9%, Paediatric 16.5%, Internal Medicine 15.9% and in Ophthalmology 4.3%. Of the antibiotics prescribed, the Access group prescribed alone were prescribed for 43% of hospitalized patients and Watch for 32%. The most used antibiotics among the admitted patients were respectively: Penicillins 43.3%, Cephalosporins 33.3% and Imidazoles 14.7%. They were indicated for antibiotic prophylaxis in surgery at 22.2%, trauma at 18.6%, antibiotic therapy in surgery at 6.4%, pneumonia at 5.9%, bone infection 5.2% and finally for gynecological pathology at 5%. Of the hospitalized patients, only 1/10th had a bacteriological examination performed Conclusion: This study allowed, to see the reality and effectiveness of antibiotic use and its preponderance over other drugs. Betalactams were the most prescribed. For a good number of patients, antibiotics were prescribed without any bacteriological evidence.