학술논문

Effectiveness of Interventions to Reduce Contact Rates during a Simulated Influenza Pandemic
Document Type
article
Source
Emerging Infectious Diseases, Vol 13, Iss 4, Pp 581-589 (2007)
Subject
influenza
models
statistical
patient isolation
quarantine
stochastic processes
Medicine
Infectious and parasitic diseases
RC109-216
Language
English
ISSN
1080-6040
1080-6059
35967595
Abstract
Measures to decrease contact between persons during an influenza pandemic have been included in pandemic response plans. We used stochastic simulation models to explore the effects of school closings, voluntary confinements of ill persons and their household contacts, and reductions in contacts among long-term care facility (LTCF) residents on pandemic-related illness and deaths. Our findings suggest that school closings would not have a substantial effect on pandemic-related outcomes in the absence of measures to reduce out-of-school contacts. However, if persons with influenzalike symptoms and their household contacts were encouraged to stay home, then rates of illness and death might be reduced by ≈50%. By preventing ill LTCF residents from making contact with other residents, illness and deaths in this vulnerable population might be reduced by ≈60%. Restricting the activities of infected persons early in a pandemic could decrease negative health impact.