학술논문

Halting the Canadian STRIDER randomised controlled trial of sildenafil for severe, early-onset fetal growth restriction: ethical, methodological, and pragmatic considerations
Document Type
article
Source
BMC Research Notes, Vol 15, Iss 1, Pp 1-6 (2022)
Subject
Fetal growth restriction
Sildenafil
Randomised controlled trial
Early trial halting
Medicine
Biology (General)
QH301-705.5
Science (General)
Q1-390
Language
English
ISSN
1756-0500
Abstract
Abstract Objectives To determine the efficacy and safety of sildenafil citrate to improve outcomes in pregnancies complicated by early-onset, dismal prognosis, fetal growth restriction (FGR). Eligibility: women ≥ 18 years, singleton, 18 + 0–27 + 6 weeks’ gestation, estimated fetal weight