학술논문
Genomic and immune landscape Of metastatic pheochromocytoma and paraganglioma
Document Type
article
Author
Bruna Calsina; Elena Piñeiro-Yáñez; Ángel M. Martínez-Montes; Eduardo Caleiras; Ángel Fernández-Sanromán; María Monteagudo; Rafael Torres-Pérez; Coral Fustero-Torre; Marta Pulgarín-Alfaro; Eduardo Gil; Rocío Letón; Scherezade Jiménez; Santiago García-Martín; Maria Carmen Martin; Juan María Roldán-Romero; Javier Lanillos; Sara Mellid; María Santos; Alberto Díaz-Talavera; Ángeles Rubio; Patricia González; Barbara Hernando; Nicole Bechmann; Margo Dona; María Calatayud; Sonsoles Guadalix; Cristina Álvarez-Escolá; Rita M. Regojo; Javier Aller; Maria Isabel Del Olmo-Garcia; Adrià López-Fernández; Stephanie M. J. Fliedner; Elena Rapizzi; Martin Fassnacht; Felix Beuschlein; Marcus Quinkler; Rodrigo A. Toledo; Massimo Mannelli; Henri J. Timmers; Graeme Eisenhofer; Sandra Rodríguez-Perales; Orlando Domínguez; Geoffrey Macintyre; Maria Currás-Freixes; Cristina Rodríguez-Antona; Alberto Cascón; Luis J. Leandro-García; Cristina Montero-Conde; Giovanna Roncador; Juan Fernando García-García; Karel Pacak; Fátima Al-Shahrour; Mercedes Robledo
Source
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Subject
Language
English
ISSN
2041-1723
Abstract
The molecular mechanisms underlying metastasis in pheochromocytoma/paraganglioma (mPPGL) remain to be explored. Here, the authors perform genomic and immunogenomic profiling of mPPGL tumors and suggest potential biomarkers for risk of metastasis and immunotherapy response.