학술논문

Modeling of three-dimensional innervated epidermal like-layer in a microfluidic chip-based coculture system
Document Type
article
Source
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Subject
Science
Language
English
ISSN
2041-1723
Abstract
Skin-nerve crosstalk is a major element of skin physiological pathology. Here the authors report a 3D innervated epidermal keratinocyte layer as a sensory neuron-epidermal keratinocyte coculture model on a microfluidic chip using the slope-based air-liquid interfacing culture and spatial compartmentalization.