학술논문
All-cause and AIDS-related mortality among people with HIV across Europe from 2001 to 2020: impact of antiretroviral therapy, tuberculosis and regional differences in a multicentre cohort studyResearch in context
Document Type
article
Author
Christian Kraef; Erich Tusch; Sabine Singh; Lars Østergaard; Gerd Fätkenheuer; Antonella Castagna; Santiago Moreno; Katharina Kusejko; Bartosz Szetela; Anastasiia Kuznetsova; Janez Tomažič; Jovan Ranin; Robert Zangerle; Fredrik Mansson; Giulia Marchetti; Stéphane De Wit; Amanda Clarke; Jan Gerstoft; Daria Podlekareva; Lars Peters; Joanne Reekie; Ole Kirk
Source
The Lancet Regional Health. Europe, Vol 44, Iss , Pp 100989- (2024)
Subject
Language
English
ISSN
2666-7762
Abstract
Summary: Background: All-cause and AIDS-mortality in Europe has been decreasing between 1996 and 2020. However, regional differences as well as their drivers remain unclear. This study investigates mortality differences and their drivers, including usage of and response to antiretroviral therapy (ART) and active tuberculosis (TB), among people with HIV across Europe. Methods: People with HIV enrolled in EuroSIDA were followed from 2001 through 2020. Immunologic-virologic status (IVS) was categorized as poor (CD4-cell count ≤350 cells/mm3 and viral load (VL) > 200 copies/ml), good (CD4 ≥ 500 and VL