학술논문
Molecular Features of the Measles Virus Viral Fusion Complex That Favor Infection and Spread in the Brain
Document Type
article
Author
Cyrille Mathieu; Francesca T. Bovier; Marion Ferren; Nicole A. P. Lieberman; Camilla Predella; Alexandre Lalande; Vikas Peddu; Michelle J. Lin; Amin Addetia; Achchhe Patel; Victor Outlaw; Barbara Corneo; N. Valerio Dorrello; Thomas Briese; Diana Hardie; Branka Horvat; Anne Moscona; Alexander L. Greninger; Matteo Porotto
Source
mBio, Vol 12, Iss 3 (2021)
Subject
Language
English
ISSN
2150-7511
Abstract
Measles virus (MeV) infection can cause serious complications in immunocompromised individuals, including measles inclusion body encephalitis (MIBE). In some cases, MeV persistence and subacute sclerosing panencephalitis (SSPE), another severe central nervous system (CNS) complication, develop even in the face of a systemic immune response.