학술논문
Mpox in people with advanced HIV infection: a global case series
Document Type
Article
Author
Mitjà, Oriol; Alemany, Andrea; Marks, Michael; Lezama Mora, Jezer I; Rodríguez-Aldama, Juan Carlos; Torres Silva, Mayara Secco; Corral Herrera, Ever Arturo; Crabtree-Ramirez, Brenda; Blanco, José Luis; Girometti, Nicolo; Mazzotta, Valentina; Hazra, Aniruddha; Silva, Macarena; Montenegro-Idrogo, Juan José; Gebo, Kelly; Ghosn, Jade; Peña Vázquez, María Fernanda; Matos Prado, Eduardo; Unigwe, Uche; Villar-García, Judit; Wald-Dickler, Noah; Zucker, Jason; Paredes, Roger; Calmy, Alexandra; Waters, Laura; Galvan-Casas, Cristina; Walmsley, Sharon; Orkin, Chloe M; Leiro, Viviana; Marchetta, Lucila; Fernandez Pardal, Patricia; Figueroa, María Inés; Cahn, Pedro; Grabmeier-Pfistershammer, Katharina; Libois, Agnes; Liesenborghs, Laurens; Grinsztejn, Beatriz; Schechter, Mauro; dos Santos de Lemos, Alberto; Furtado Costa, Alvaro; Queiroz Rocha, Simone; Valdez Madruga, José; S. Tan, Darrell H.; Mishra, Sharmistha; Shah, Shreya; Jorquera, Camila; Castillo, Alberto; Carrión, Mauricio; Cevallos, Nelson; Palich, Romain; Pourcher, Valerie; Rubenstein, Emma; Migaud, Pascal; Boesecke, Christoph; Hoffmann, Christian; Protopapas, Konstantinos; Nozza, Silvia; Cattelan, Anna Maria; Mussini, Cristina; d'Arminio Monforte, Antonella; Cruz Flores, Raúl Adrian; Pérez Barragán, Edgar; Rodríguez Guzmán, Alma Leticia; Ogoina, Dimie; Chika-Igwenyi, Nneka Marian; Chizaram, Onyeaghala; Valverde López, Jenny; García Tello, Angelica; Ubals, Maria; Vall, Martí; Mendoza, Adrià; Suñer, Clara; Clotet, Bonaventura; Bechini, Jordi; Lepe, Jose A; Navarro-Amuedo, M. Dolores; Bernadino, Jose Ignacio; Català, Alba; Tarín Vicente, Eloy José; González Rodríguez, Borja; Rodriguez-Mercader, Sergi; Sánchez-Martinez, Francisca; Cañas-Ruano, Esperanza; Parra-Navarro, Laura; Filén, Finn; Tallón de Lara, Carmen; Braun, Dominique; Piezzi, Vanja; Burkhard, Michael; Kovari, Helen; Mönch, Anja; Dunning, Jake; Simoes, Pedro; Nori, Achyuta; Keegan, Sarah; Thornhill, John P; Apea, Vanessa; Noori, Teymur; Jones, Joyce L.; Judson, Seth; Gilliams, Elizabeth A.; Hammill, Matthew; Keruly, Jeanne; Henao Martínez, Andrés F.; Lin, Aung; So, Jessica; Davar, Kusha; Villareal, Diana
Source
The Lancet; March 2023, Vol. 401 Issue: 10380 p939-949, 11p
Subject
Language
ISSN
01406736; 1474547X
Abstract
People living with HIV have accounted for 38–50% of those affected in the 2022 multicountry mpox outbreak. Most reported cases were in people who had high CD4 cell counts and similar outcomes to those without HIV. Emerging data suggest worse clinical outcomes and higher mortality in people with more advanced HIV. We describe the clinical characteristics and outcomes of mpox in a cohort of people with HIV and low CD4 cell counts (CD4 <350 cells per mm3).