학술논문
Pharmacological blood pressure lowering for primary and secondary prevention of cardiovascular disease across different levels of blood pressure: an individual participant-level data meta-analysis
Document Type
Article
Author
Rahimi, Kazem; Bidel, Zeinab; Nazarzadeh, Milad; Copland, Emma; Canoy, Dexter; Ramakrishnan, Rema; Pinho-Gomes, Ana-Catarina; Woodward, Mark; Adler, Amanda; Agodoa, Larry; Algra, Ale; Asselbergs, Folkert W; Beckett, Nigel S; Berge, Eivind; Black, Henry; Brouwers, Frank P J; Brown, Morris; Bulpitt, Christopher J; Byington, Robert P; Cushman, William C; Cutler, Jeffrey; Devereaux, Richard B; Dwyer, Jamie; Estacio, Ray; Fagard, Robert; Fox, Kim; Fukui, Tsuguya; Gupta, Ajay K; Holman, Rury R; Imai, Yutaka; Ishii, Masao; Julius, Stevo; Kanno, Yoshihiko; Kjeldsen, Sverre E; Kostis, John; Kuramoto, Kizuku; Lanke, Jan; Lewis, Edmund; Lewis, Julia B; Lievre, Michel; Lindholm, Lars H; Lueders, Stephan; MacMahon, Stephen; Mancia, Giuseppe; Matsuzaki, Masunori; Mehlum, Maria H; Nissen, Steven; Ogawa, Hiroshi; Ogihara, Toshio; Ohkubo, Takayoshi; Palmer, Christopher R; Patel, Anushka; Pfeffer, Marc Allan; Pitt, Bertram; Poulter, Neil R; Rakugi, Hiromi; Reboldi, Gianpaolo; Reid, Christopher; Remuzzi, Giuseppe; Ruggenenti, Piero; Saruta, Takao; Schrader, Joachim; Schrier, Robert; Sever, Peter; Sleight, Peter; Staessen, Jan A; Suzuki, Hiromichi; Thijs, Lutgarde; Ueshima, Kenji; Umemoto, Seiji; van Gilst, Wiek H; Verdecchia, Paolo; Wachtell, Kristian; Whelton, Paul; Wing, Lindon; Yui, Yoshiki; Yusuf, Salim; Zanchetti, Alberto; Zhang, Zhen-Yu; Anderson, Craig; Baigent, Colin; Brenner, Barry Morton; Collins, Rory; de Zeeuw, Dick; Lubsen, Jacobus; Malacco, Ettore; Neal, Bruce; Perkovic, Vlado; Rodgers, Anthony; Rothwell, Peter; Salimi-Khorshidi, Gholamreza; Sundström, Johan; Turnbull, Fiona; Viberti, Giancarlo; Wang, Jiguang; Chalmers, John; Teo, Koon K; Pepine, Carl J; Davis, Barry R
Source
The Lancet; May 2021, Vol. 397 Issue: 10285 p1625-1636, 12p
Subject
Language
ISSN
01406736; 1474547X
Abstract
The effects of pharmacological blood pressure lowering at normal or high-normal blood pressure ranges in people with or without pre-existing cardiovascular disease remains uncertain. We analysed individual participant data from randomised trials to investigate the effects of blood pressure lowering treatment on the risk of major cardiovascular events by baseline levels of systolic blood pressure.