학술논문
Determination of fructose 2,6-bisphosphate in human lymphocytes is a potential laboratory test in diabetology
Document Type
Article
Author
Source
Bulletin of Experimental Biology and Medicine; September 1996, Vol. 122 Issue: 3 p950-952, 3p
Subject
Language
ISSN
00074888; 15738221
Abstract
Abstract: The conventional micromethod of fructose 2,6-bisphosphate (F-2,6-P2 ) determination is optimized for human peripheral blood lymphocytes. The F-2,6-P2 content in lymphocytes of healthy subjects is 0.8±0.2 pmol/106 cells or 6.7±1.1 pmol/mg protein. Preliminary findings show a decrease in the F-2,6-P2 content in lymphocytes from patients with severe diabetes mellitus.