학술논문
Dysregulated expression of amino-acid and glucose transporters on circulating plasma cells in septic shock patients: a preliminary study.
Document Type
Article
Author
Source
Subject
*PLASMA cells
*SEPTIC shock
*GLUCOSE transporters
*REGULATORY B cells
*B cells
*AMINO acid metabolism
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Language
ISSN
2197-425X
Abstract
We first confirmed the occurrence of sepsis-induced immune alterations in patients with decreased monocyte HLA-DR expression, reduced CD4 SP + sp T cell count (Additional file 1: Table S1), and increased proportion of circulating plasma cells at D3-4 after sepsis (Fig. As the induction of regulatory plasma cells has been described in mice and human after sepsis [[5]], results from the current study suggested that metabolic alteration may represent a novel mechanism of regulatory plasma cell induction in sepsis. [Extracted from the article]