학술논문
Structural elucidation and complete NMR spectral assignments of Monascus monacolin analogues.
Document Type
Article
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Source
Subject
Language
ISSN
0749-1581
Abstract
Three new monacolin analogues, 3,6‐dihydroxy‐monacolin P (1 ), 6‐methoxy monacolin S (2 ), and 6‐methoxy dehydromonacolin S (3 ), were isolated from a fraction that strongly inhibited 3‐hydroxy‐3‐methylglutaryl‐CoA reductase from the ethyl acetate portion of red yeast rice ethanol extract. Their structures were determined through a combination of 1D and 2D NMR experiments, mass spectrometry analysis, and known literature reports. [ABSTRACT FROM AUTHOR]