학술논문
Angiogenesis Inhibitors as Anti-Cancer Therapy Following Renal Transplantation: A Case Report and Review of the Literature.
Document Type
Article
Author
Source
Subject
*NEOVASCULARIZATION inhibitors
*DRUG side effects
*LITERATURE reviews
*DRUG interactions
*VASCULAR endothelial growth factors
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Language
ISSN
1198-0052
Abstract
Solid organ transplant recipients on long-term immunosuppressive medication are at increased risk of developing malignancy, and treatment of advanced cancers with angiogenesis inhibitors in this context has not been widely studied. We present a case of recurrent high-grade serous ovarian carcinoma treated with paclitaxel and bevacizumab in the context of prior renal transplantation where the patient responded well to treatment with controlled toxicities, discussing the potential for increased rates of adverse events and drug interactions in this select population. [ABSTRACT FROM AUTHOR]