학술논문
Colchicine: an ancient drug with novel applications.
Document Type
Article
Author
Source
Subject
*COLCHICINE
*FAMILIAL Mediterranean fever
*AMYLOIDOSIS
*DRUG administration
*EPIDERMOLYSIS bullosa
*THERAPEUTICS
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*
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Language
ISSN
0007-0963
Abstract
Summary: Colchicine is a treatment for gout that has been used for more than a millennium. It is the treatment of choice for familial Mediterranean fever and its associated complication, amyloidosis. The 2009 U.S. Food and Drug Administration approval of colchicine as a new drug had research consequences. Recent investigations with large cohorts of patients with gout who have been taking colchicine for years have demonstrated novel applications within oncology, immunology, cardiology and dermatology. Some emerging dermatological uses include the treatment of epidermolysis bullosa acquisita, leucocytoclastic vasculitis, aphthous stomatitis and others. In this work we relate the history and the new horizon of this ancient medicine. [ABSTRACT FROM AUTHOR]