학술논문
An electrochemiluminescence dual "turn-on" strategy for alkaline phosphatase detection using a dual quenching Ru(bpy)3 2+ encapsulated zeolite imidazole metal organic framework.
Document Type
Article
Author
Source
Subject
*METAL-organic frameworks
*ALKALINE phosphatase
*ELECTROCHEMILUMINESCENCE
*FLUORESCENCE resonance energy transfer
*IMIDAZOLES
*ELECTROLUMINESCENT polymers
*ZEOLITES
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Language
ISSN
1359-7345
Abstract
An electrochemiluminescence dual "turn-on" strategy is first designed to detect alkaline phosphatase (ALP) using a dual quenching Ru(bpy)32+ encapsulated zeolite imidazole metal organic framework (Ru(bpy)32+@ZIF-90). Resonance energy transfer (ECRET) makes ECL "turn-off". Ascorbic acid 2-phosphate is hydrolyzed into PO43− and ascorbic acid (AA) by ALP. PO43− decomposes Ru(bpy)32+@ZIF-90 and AA prevents ECRET, which makes ECL "turn-on" again. [ABSTRACT FROM AUTHOR]